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Antidepressant About as Effective as Estrogen for Menopausal Symptoms, Study Finds

In the first randomized trial comparing estrogen (estradiol 0.5 mg/day) and an antidepressant (venlafaxine 75 mg/day) for treating the hot flashes and night sweats common in menopause, both agents were found to be effective and well tolerated. "Low-dose oral estradiol and venlafaxine are effective treatments for [vasomotor symptoms] in women during midlife. While the efficacy of low-dose estradiol may be slightly superior to that of venlafaxine, the difference is small and of uncertain clinical relevance," the researchers said. The study was headed by Hadine Joffe, M.D., an associate professor of...

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Published By: Psychiatric News - Yesterday