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Brain Imaging During Memory Task May Predict Response to Antidepressant

Brain imaging of activity in the visual cortex while performing working-memory tasks may prove a biomarker for response to an experimental rapid-acting antidepressant, according to a National Institute of Mental Health (NIMH) study in the Journal of the American Medical Association.

Scopolamine, better known as a treatment for motion sickness, has been under study since its fast-acting antidepressant properties were first reported in 2006. But not all patients respond. So Maura Furey, Ph.D., and colleagues developed a strategy for identifying patients likely to respond to the drug. The acetylcholine system, on which...

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Published By: Psychiatric News - Tuesday, 5 February