Creatine Supplement to SSRI Antidepressant May Speed Recovery From Depression

Adding creatine—a dietary supplement—to treatment of depression with an SSRI antidepressant may be a promising therapeutic approach that speeds response to the medication, according to a report in the American Journal of Psychiatry.

Korean and American investigators enrolled 52 women with major depressive disorder in an 8-week double-blind placebo-controlled clinical trial and randomly assigned them to receive escitalopram—an SSRI antidepressant—in addition to either creatine or placebo. Efficacy was primarily assessed by changes in the Hamilton Depression Rating Scale (HAM-D).

They found that in comparison with the placebo group, patients receiving creatine augmentation...

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Published By: Psychiatric News - Yesterday