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Gene Variations in Alzheimer's Show Racial Variations, Study Finds

Many of the same genes associated with increased risk for Alzheimer's disease among people of European ancestry are also present in African Americans, but effect sizes vary between the two groups, according to a study of thousands of individuals published in today's Journal of the American Medical Association.

Researchers led by Richard Mayeux, M.D., M.Sc., a professor of neurology, psychiatry, and epidemiology at Columbia University, studied data from 1,968 African Americans with Alzheimer's disease and 3,928 control subjects. The most significant gene associated with the disorder was APOE, a previously well-known risk factor....

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Published By: Psychiatric News - Wednesday, 10 April